Q As shown in the figure, cyanide inhibits the electron transport chain by competing with O2 molecules for the cytochrome c oxidase heme group. Carbon monoxide (CO) has a similar effect. Both cyanide and carbon monoxide cause poisoning in victims of smoke inhalation. Predict the effects of these poisons on the following properties of mitochondria just after exposure: the pH of the intermembrane space, the concentration of NADH, and the rate of production of ATP in the matrix. Justify your predictions.
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